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Alchemist Guide for Diablo 4 (Season 4)

How to upgrade potions, craft elixirs, refine mats, and ignite incenses!

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Neviriah

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Introduction

The Alchemist is an important NPC throughout your adventures across Sanctuary. This guide covers the benefits of upgrading potions, crafting Elixirs, refining materials, or crafting Incense and consumables. Upgrading the character’s Healing Potions is very important, allowing you to improve the gameplay experience and progress further in the game. 

How to Unlock the Alchemist

Upon reaching Level 10, you will have to complete a priority quest leading you to visit Veroka, the Alchemist in Kyovashad. In order to complete the quest, Weak healing potions will have to be upgraded into Tiny Healing Potion, for the price of 10 Bundled Herbs.

Alchemists are located in any major city of each zone. They are indicated on the map by a mortar and pestle icon:

How to Upgrade Potions

As your character progresses, you have the ability to upgrade the Healing potion. Each upgrade enhances the Healing Vial’s ability to restore a greater amount of Life when it is used.

Make sure to visit the Alchemist in each main town and check for any new available upgrades whenever the character reaches a new level milestone. You can check out our Diablo 4 zones overview to quickly see all the main towns of each area.

Below are the various upgrades, along with their resource cost and the improved effects they provide:

Potion TypeResources neededEffect
Weak Healing Potion
Level 1
Available directly at Level 1Heals 17 Life instantly and 35% Life over 3 seconds.
Tiny Healing Potion
Unlocks at Level 10
• 10 Bundled HerbsBundled Herbs
• 5,000 Gold
Heals 48 Life Instantly and 35% Life over 3 seconds.
Minor Healing Potion
Unlocks at Level 20
• 35 Bundled HerbsBundled Herbs
• 10,000 Gold
Heals 80 Life instantly and 35% Life over 3 seconds.
Light Healing Potion
Unlocks at Level 30
• 45 Bundled HerbsBundled Herbs
• 150,000 Gold
Heals 141 Life instantly and 35% Life over 3 seconds.
Moderate Healing Potion
Unlocks at Level 45
• 70 Bundled HerbsBundled Herbs
• 500,000 Gold
Heals 255 Life instantly and 35% Life over 3 seconds.
Strong Healing Potion
Unlocks at Level 60
• 110 Bundled HerbsBundled Herbs
• 15 AngelbreathAngelbreath
• 1,000,000 Gold
Heals 378 Life instantly and 35% Life over 3 seconds.
Greater Healing Potion
Unlocks at Level 70
• 180 Bundled HerbsBundled Herbs
• 20 AngelbreathAngelbreath
• 5 Forgotten SoulForgotten Soul
• 3,000,000 Gold
Heals 559 Life instantly and 35% Life over 3 seconds.
Major Healing Potion
Unlocks at Level 80
• 290 Bundled HerbsBundled Herbs
• 25 AngelbreathAngelbreath
• 10 Forgotten SoulForgotten Soul
• 5,000,000 Gold
Heals 827 Life instantly and 35% Life over 3 seconds.
Superior Healing Potion
Unlocks at Level 90
• 425 Bundled HerbsBundled Herbs
• 30 AngelbreathAngelbreath
• 20 Forgotten SoulForgotten Soul
• 7,000,000 Gold
Heals 1,274 Life instantly and 35% Life over 3 seconds.

Craft Elixirs

Alchemists have the ability to brew various Elixirs, offering an experience boost and a stat boost for a duration of 30 minutes. Each Elixir requires a specific amount of gold and materials to craft, as the Alchemists require compensation for their services. These Elixirs can prove particularly valuable during World Boss fights or challenging high-end content. 

As your character gains levels, it becomes possible to craft stronger versions of each Elixir, which provide greater bonuses. However, keep in mind that crafting these enhanced versions requires higher crafting costs.

Craft Incenses

Incenses function similarly to Elixirs, providing temporary bonuses to players. However, the key distinction is that incenses are particularly beneficial when you are part of a party, as the buffs they provide extend to the entire party. The first incense becomes available at Level 45, and only one incense can be active at a time.

Moreover, Incenses are categorized into different tiers known as types. It is important to remember that only one type of incense can be active simultaneously. However, this also creates an opportunity for players to use both a Type I, Type II and Type III Incense concurrently, as long as they are distinct types.

Below is a list of incenses and their respective bonuses:

IncenseEffectTier / TypeMaterials needed to craft
Chorus of WarChorus of War,
Requires Level 100
Increases all stats by 40 and Crit and Overpower Damage by 5% for every nearby player and increases Experience by 5%. Lasts 20 minutes.Type III• 100 Bundled HerbsBundled Herbs
• 10 AngelbreathAngelbreath
• 10 Veiled CrystalVeiled Crystal
• 100 Ruby Fragments
• 100 Sapphire Fragments
• 6,000 Gold
Spirit DanceSpirit Dance,
Requires Level 80
Increases Chance to Dodge by 5% for every nearby player and increases Experience by 5%. Lasts 20 minutes.Type II• 90 Bundled HerbsBundled Herbs
• 9 AngelbreathAngelbreath
• 9 Veiled CrystalVeiled Crystal
• 5,000 Gold
Soothing SpicesSoothing Spices,
Requires Level 75
Increases Resistance to All Elements by +10%, Maximum Resistance for All Elements by +1%, and Armor by 150 for every nearby player and increases Experience by 5%. Lasts 20 minutes.Type II• 85 Bundled HerbsBundled Herbs
• 8 AngelbreathAngelbreath
• 7 Veiled CrystalVeiled Crystal
• 85 Diamond Fragments
• 85 Skull Fragments
• 4,500 Gold
Scents of the Desert AfternoonScents of the Desert Afternoon,
Requires Level 70
Increases Thorns by 250 for every nearby player and increases Experience by 5%. Lasts 20 minutes.Type II• 80 Bundled HerbsBundled Herbs
• 7 AngelbreathAngelbreath
• 6 Veiled CrystalVeiled Crystal
• 160 Emerald Fragments
• 4,000 Gold
Spiral MorningSpiral Morning,
Requires Level 65
Increases all stats by 15 for every nearby player and increases Experience by 5%. Lasts 20 minutes.Type II• 80 Bundled HerbsBundled Herbs
• 6 AngelbreathAngelbreath
• 6 Veiled CrystalVeiled Crystal
• 3,500 Gold
Reddamine BuzzReddamine Buzz,
Requires Level 60
Increases Maximum Life by 500 for every nearby player and increases Experience by 5%. Lasts 20 minutes.Type II• 75 Bundled HerbsBundled Herbs
• 5 AngelbreathAngelbreath
• 4 Veiled CrystalVeiled Crystal
• 140 Ruby Fragments
• 3,000 Gold
Desert EscapeDesert Escape,
Requires Level 55
Increases Fire, Cold, and Shadow Resistances by +15% and their Maximum Resistances by +2% for every nearby player and increases Experience by 5%. Lasts 20 minutes.Type I• 70 Bundled HerbsBundled Herbs
• 4 AngelbreathAngelbreath
• 3 Veiled CrystalVeiled Crystal
• 50 Amethyst Fragments
• 50 Sapphire Fragments
• 2,500 Gold
Storm of the WildsStorm of the Wilds,
Requires Level 55
Increases Lightning, Cold, and Poison Resistances by +15% and their Maximum Resistances by +2% for every nearby player and increases Experience by 5%. Lasts 20 minutes.Type I• 65 Bundled HerbsBundled Herbs
• 4 AngelbreathAngelbreath
• 3 Veiled CrystalVeiled Crystal
• 50 Emerald Fragments
• 50 Topaz Fragments
• 2,500 Gold
Ancient TimesAncient Times,
Requires Level 50
Increases Strength by 25 for every nearby player and increases Experience by 5%. Lasts 20 minutes.Type I• 60 Bundled HerbsBundled Herbs
• 2 Veiled CrystalVeiled Crystal
• 35 Ruby Fragments
• 2,500 Gold
Blessed GuideBlessed Guide,
Requires Level 50
Increases Willpower by 25 for every nearby player and increases Experience by 5%. Lasts 20 minutes.Type I• 60 Bundled HerbsBundled Herbs
• 2 Veiled CrystalVeiled Crystal
• 35 Amethyst Fragments
• 2,000 Gold
Queen's SupremeQueen’s Supreme,
Requires Level 50
Increases Dexterity by 25 for every nearby player and increases Experience by 5%. Lasts 20 minutes.Type I• 60 Bundled HerbsBundled Herbs
• 2 Veiled CrystalVeiled Crystal
• 35 Emerald Fragments
• 2,000 Gold
Sage's WhisperSage’s Whisper,
Requires Level 50
Increases Intelligence by 25 for every nearby player and increases Experience by 5%. Lasts 20 minutes.Type I• 60 Bundled HerbsBundled Herbs
• 2 Veiled CrystalVeiled Crystal
• 35 Topaz Fragments
• 2,000 Gold
Song of the MountainSong of the Mountain,
Requires Level 45
Increases Armor by 200 for every nearby player and increases Experience by 5%. Lasts 20 minutes.Type I• 55 Bundled HerbsBundled Herbs
• 1 Veiled CrystalVeiled Crystal
• 30 Skull Fragments
• 1,500 Gold

Transmutation

At the Alchemist, you can also transmute multiple items to create new ones. This includes Masterworking Materials, Summoning Materials, and Uber Uniques.

For example, to transmute a Summoning Item you will need various materials and components like Veiled CrystalVeiled Crystal, Abstruse SigilAbstruse Sigil, Baleful FragmentBaleful Fragment, and Coiling WardCoiling Ward to transmute and craft the desired items.

Craft Uber Uniques

With Patch 1.3.2, the Refine Resources tab was renamed “Transmute” and the option to craft Uber Uniques in exchange for 5 Resplendent SparkResplendent Spark was added. Resplendent Sparks can be obtained by salvaging other Uber Uniques.

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