Cyrene Best Team Compositions & Character Synergies

Honkai: Star Rail
Last Updated: Today at 12:00

Introductions

Welcome to our team composition guide for Cyrene in Honkai: Star Rail. In this guide, we'll explore the best teams to build for Cyrene, including recommended team compositions, character synergies and everything you need to know to let your Cyrene teams shine.

Best Synergies for Cyrene

Cyrene has great synergy with each of the Chrysos Heirs, but she does have greater synergy with some specific characters more so than others. We will add more detailed information about each Chrysos Heir shortly.

Cyrene's Best Teams

Cyrene is a powerful support unit that is best used alongside other Remembrance characters or Chrysos Heir for the most success.

This is not a comprehensive list of teams. The inclusion or exclusion of any given team does not necessarily reflect its power level. We have included several example teams that are more F2P friendly using 4★ characters that are lower power than the 5★ teams as examples. The Sustain Character in each team can be swapped out but we would strongly recommend using Hyacine for Health Scaling Teams and Dan Heng • Permansor Terrae for ATK Scaling Teams if they are available as they are significantly better than any alternative.

Castorice Evernight Cyrene Hyacine
Evernight Cyrene Remembrance Trailblazer Hyacine
Anaxa Cerydra Cyrene Dan Heng • Permansor Terrae
Mydei Cerydra Cyrene Hyacine
Aglaea Sunday Cyrene Dan Heng • Permansor Terrae
Hysilens Kafka Cyrene Dan Heng • Permansor Terrae
Phainon Cerydra Cyrene Dan Heng • Permansor Terrae
Saeldur
Staff Author
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This guide was written by Saeldur, expert Honkai: Star Rail theorycrafter and guide writer for Icy Veins. Saeldur is a high-end HSR player with a deep understanding of the various characters while also clearing PF, MoC and AS when each cycle releases.

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Changelog

  • 04 Nov. 2025: Build Guide for Cyrene added.
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