Cyrene Best Builds, Teams & Relics

Honkai: Star Rail
Last Updated: Today at 12:00

Introductions

Cyrene is a 5★ Ice Character following the Path of Remembrance. Cyrene is an incredibly potent healer that boosts team survivability and can sustain your Team through the harshest encounters.
Our Cyrene Build Guide will show you the best Lightcones, Relics and Team Compositions build the best Cyrene you can.

Cyrene's Best Light Cone

Listed below are Cyrene's best lightcones to use.

This Love, Forever
S1
Increases the wearer's SPD by 18.0 / 21.0 / 24.0 / 27.0 / 30.0%. When the wearer's memosprite uses a Memosprite Skill on an ally, gains "Blank," which increases DMG taken by all enemies by 10.0 / 12.0 / 14.0 / 16.0 / 18.0%. When the wearer's memosprite uses a Memosprite Skill on an enemy, gains "Verse," which increases CRIT DMG of all allies by 16.0 / 19.0 / 22.0 / 25.0 / 28.0%. When the wearer's memosprite has both "Blank" and "Verse," increases the effects of "Blank" and "Verse" by 60.0 / 65.0 / 70.0 / 75.0 / 80.0%.
This is Cyrene's Signature Lightcone and is her best Lightcone by a significant margin. This Lightcone has very high base HP, SPD %, a Damage Vulnerability for all enemies and a large CRIT DMG boost for all allies. This Lightcone is the best for both Team DPS and Cyrene's personal damage.
Long May Rainbows Adorn the Sky
S1
Increases the wearer's SPD by 18.0 / 21.0 / 24.0 / 27.0 / 30.0%. When the wearer uses Basic ATK, Skill, or Ultimate, consumes all allies' HP equal to 1.0 / 1.3 / 1.5 / 1.8 / 2.0% of their current HP, and after the next attack of the wearer's memosprite, enables it to additionally deal 1 instance of Additional DMG equal to 250.0 / 312.5 / 375.0 / 437.5 / 500% of the total consumed HP to the attacked target, with the damage type based on the memosprite's type. Then, the total consumed HP is reset. When the wearer's memosprite uses Memosprite Skill, increases the DMG taken by all enemies by 18.0 / 22.5 / 27.0 / 31.5 / 36.0%, lasting for 2 turn(s). Effects of the same type cannot stack.

Sources: Event Warp (limited)
Hyacine's Signature Lightcone and Cyrene's Second Best Lightcone. This Lightcone has higher base HP, a large boost to SPD % and a potent increased Damage Taken Debuff for all enemies.
We do not suggest giving this Lightcone to Cyrene as it would be best used on Hyacine for overall team DPS. This Lightcone is not stackable so don't run two copies.
Time Woven Into Gold
S1
Increases the wearer's base SPD by 12 / 14 / 16 / 18 / 20. After the wearer and the wearer's memosprite attacks, the wearer gains 1 stack of "Brocade." Each stack of "Brocade" increases the wearer's and their memosprite's CRIT DMG by 9.0 / 10.5 / 12.0 / 13.5 / 15.0%, stacking up to 6 time(s). When reaching maximum stacks, each "Brocade" stack additionally increases Basic ATK DMG dealt by 9.0 / 10.5 / 12.0 / 13.5 / 15.0%.

Sources: Event Warp (limited)
Aglaea's Signature Lightcone. This Lightcones effects only affect Cyrene and do not boost team damage however the buffs provided by this Lightcone are massive. You get an increase to Base SPD, a massive CRIT DMG boost, and a boost to Basic ATK DMG. Approximately 30% of Cyrene's damage comes from her Basic ATK.
If you still play Aglaea then we do not suggest giving this to Cyrene. Running this over Memory's Curtain Never Falls would be a small increase in damage.
To Evernight's Stars
S1
Increases the wearer's Max HP by 30.0 / 37.5 / 45.0 / 52.5 / 60.0%. When the wearer's memosprite uses an ability, the wearer gains "Noctis." While the wearer has "Noctis," the DMG dealt by all ally memosprites ignores 20.0 / 22.5 / 25.0 / 27.5 / 30.0% of the targets' DEF. Increases the DMG dealt by the wearer and their memosprite by 30.0 / 37.5 / 45.0 / 52.5 / 60.0%. When the wearer's memosprite disappears, the wearer recovers 8 / 10 / 12 / 14 / 16 Energy. Effects of the same type cannot stack.

Sources: Event Warp (limited)
Evernight's Signature Lightcone. This Lightcone provides a large DEF % Ignore to all allied Memosprites which is the main bulk of this Lightcones Power. In non-Memosprite Teams this Lightcone is notably weaker.
This Lightcone also has higher Base HP, a HP % boost and a DMG % boost to further boost Cyrene's personal damage.
We do not suggest giving this to Cyrene if you have Evernight as it would be best used on Evernight. This Lightcone cannot stack, so do not run two copies.
Memory's Curtain Never Falls
S5
Increases the wearer's SPD by 6.0 / 7.5 / 9.0 / 10.5 / 12.0%. After the wearer uses Skill, increases the DMG dealt by all allies by 8.0 / 10.0 / 12.0 / 14.0 / 16.0%, lasting for 3 turn(s).

Sources: Herta's Store
This is the Herta's Store 5★ Remembrance Lightcone. This Lightcone has a large increase to SPD % which is Cyrene's most important stat. This also provides DMG % to allies makes it a strong option for Team Damage.
Sweat Now, Cry Less
S5
Increases the wearer's CRIT Rate by 12.0 / 14.0 / 16.0 / 18.0 / 20.0%. When the wearer's memosprite is on the field, increases the DMG dealt by the wearer and their memosprite by 24.0 / 27.0 / 30.0 / 33.0 / 36.0%.

Sources: Nameless Glory
This is a 4★ Battlepass Lightcone that provides a large boost to personal DMG granting 20% CRIT Rate and 36% DMG at S5. This Lightcone does not provide any increase to Team DPS and does not boost SPD, which is Cyrene's best stat making it worse than other options. We do not recommend going for this Lightcone specifically for Cyrene. This Lightcone does not boost SPD which makes gearing significantly harder.
The Flower Remembers
S5
Increases the wearer's CRIT DMG by 24.0 / 28.0 / 32.0 / 36.0 / 40.0%. The CRIT DMG dealt by the wearer's memosprite increases by 24.0 / 30.0 / 36.0 / 42.0 / 48.0%.

Sources: Nameless Glory
This 4★ Battlepass Lightcone is less powerful than the other Battle Pass Lightcone, Sweat Now, Cry Less so we do not recommend going for this Lightcone specifically for Cyrene. This Lightcone does not boost SPD which makes gearing significantly harder.
Make Farewells More Beautiful
S1
Increases the wearer's Max HP by 30.0 / 37.5 / 45.0 / 52.5 / 60.0%. When the wearer or their memosprite loses HP during their own turn, the wearer gains "Death Flower." "Death Flower" allows the wearer and their memosprite to ignore 30.0 / 35.0 / 40.0 / 45.0 / 50.0% of the target's DEF when dealing DMG, lasting for 2 turn(s). When the wearer's memosprite disappears, advances the wearer's action by 12.0 / 15.0 / 18.0 / 21.0 / 24.0%. This effect can only trigger up to 1 time, and the trigger count resets every time the wearer uses Ultimate.

Sources: Event Warp (limited)
Castorice's Signature Lightcone. This Lightcone has gets all of its power from high Base HP and boost to HP%. Cyrene will not be able to gain the effects of the DEF Ignore as she does not lose Health on her own turns. This Lightcone does not boost SPD which makes gearing significantly harder.
We do not suggest giving this to Cyrene if you have Castorice as it would be best used on Castorice.

Best Relics and Planar Ornaments for Cyrene

Best Relics for Cyrene

These are the best Relic Sets to build for Cyrene.

World-Remaking Deliverer
2-Piece Set: Increases CRIT Rate by 8.0%.
4-Piece Set: After the wearer uses Basic ATK or Skill, if the wearer's memosprite is on the field, increases Max HP of the wearer and their memosprite by 24.0%, and increases all allies' dealt DMG by 15.0%, lasting until after the wearer's next use of Basic ATK or Skill.
This is Cyrene's best Relic Set to build and but is only slightly ahead of any other options. This provides a large increase to team DPS via the Team-wide DMG Buff while also boosting Cyrene's personal damage with the CRIT Rate % from the 2pc, and a big HP% boost from the 4pc. Other options may be stronger if you are struggling to get SPD as it is extremely important you get SPD on Cyrene above all else.
Eagle of Twilight Line
2-Piece Set: Increases Wind DMG by 10.0%.
4-Piece Set: After the wearer uses their Ultimate, their action is Advanced Forward by 25.0%.
This is a more niche Relic Set to build but can give amazing results with the right setups. After Transforming Cyrene uses her Ultimate extremely frequently (at least once every 2 Turns, in Memosprite teams it can be even faster) so Eagle gives you more turns over an entire fight than running SPD sets. It is still extremely important to get to 180 SPD when running Eagle for Cyrene's A2 Trace Causality in Trichotomy. This set is best used when paired with Chyrsos heirs with amazing repeatable bonuses like Mydei or Anaxa.
Messenger Traversing Hackerspace
2-Piece Set: Increases SPD by 6.0%.
4-Piece Set: When the wearer uses their Ultimate on an ally, SPD for all allies increases by 12.0% for 1 turn(s). This effect cannot be stacked.
This is a competitive option for Cyrene that provides more SPD% making it easier to reach her 180 SPD breakpoint for Cyrene's A2 Trace Causality in Trichotomy. After Cyrene transforms she use her Ultimate very frequently providing good uptime on the 12% SPD Buff.
Sacerdos' Relived Ordeal
2-Piece Set: Increases SPD by 6.0%.
4-Piece Set: When using Skill or Ultimate on one ally target, increases the ability target's CRIT DMG by 18.0%, lasting for 2 turn(s). This effect can stack up to 2 time(s).
This is another viable option for easier gearing since the 2pc provides 6% SPD. Cyrene will maintain the CRIT DMG bonus from the 4pc on herself giving her 36% CRIT DMG at all times as both her Skill and Ultimate count using it on herself.
Messenger Traversing Hackerspace Warrior Goddess of Sun and Thunder
2-Piece Set: Increases SPD by 6.0%.
4-Piece Set: When the wearer uses their Ultimate on an ally, SPD for all allies increases by 12.0% for 1 turn(s). This effect cannot be stacked.
2-Piece Set: Increases SPD by 6.0%.
4-Piece Set: When the wearer or their memosprite provides healing to ally targets other than themselves, the wearer gains "Gentle Rain," which lasts for 2 turn(s) and can only trigger once per turn. While the wearer has "Gentle Rain," SPD increases by 6.0% and all allies' CRIT DMG increases by 15.0%. This effect cannot stack.
Running 2 of the 6% SPD sets (Messenger Traversing Hackerspace, Warrior Goddess of Sun and Thunder or Sacerdos' Relived Ordeal) is a good option if you are struggling to get to the 180 SPD breakpoint for Cyrene's A2 Trace Causality in Trichotomy.

Best Planar Ornaments

Amphoreus, The Eternal Land
2-Piece Set: Increases the wearer's CRIT Rate by 8.0%. While the wearer's memosprite is on the field, increases all allies' SPD by 8.0%. This effect cannot be stacked.
This is Cyrene's best-in-slot Planar Ornament. This Planar Ornament provides 8% CRIT Rate for Cyrene always and 8% SPD for all allies after Cyrene uses her Ultimate and summons her Memosprite. Your team can only benefit from one Amphoreus Planar Ornament set so it might be beneficial to get it from a character who has their Memosprite active immediately like Remembrance Trailblazer.
Sprightly Vonwacq
2-Piece Set: Increases the wearer's Energy Regeneration Rate by 5.0%. When the wearer's SPD reaches 120 or higher, the wearer's action is Advanced Forward by 40.0% immediately upon entering battle.
This is a potent alternative to Amphoreus, The Eternal Land that makes allows you to get 3 turns in the 0th cycle at 180 SPD instead of 200. Additionally at 184 SPD you can get two turns in the 1st cycle too. Using Vonwacq will slightly lower the damage that she provides compared to Amphoreus, The Eternal Land but getting more turns will allow her to build Recollection towards her Ultimate faster which is the main source of her DPS output for a team.
Forge of the Kalpagni Lantern Giant Tree of Rapt Brooding
2-Piece Set: Increases the wearer's SPD by 6.0%. When the wearer hits an enemy target that has Fire Weakness, the wearer's Break Effect increases by 40.0%, lasting for 1 turn(s).
2-Piece Set: Increases the wearer's SPD by 6.0%. When the wearer's SPD is 135/180 or higher, the wearer and their memosprite's Outgoing Healing increases by 12.0%/20.0%.
These sets provide a static 6% SPD which is valuable if you are struggling to reach the 180 SPD breakpoint or the 200 SPD breakpoints as these are the most impactful things to do for Cyrene and getting CRIT Rate, CRIT DMG and more Health is a luxury. This is especially useful if you are running Amphoreus, The Eternal Land as otherwise Amphoreus, The Eternal Land may still be a better option even if you lack the SPD in the first cycle.

Cyrene's Stat Priority

Body
CRIT DMG
>
HP%
Feet
SPD
Planar Sphere
Ice DMG Boost
>
HP%
Link Rope
HP%
Stat Priority
SPD
>
CRIT Rate
>
CRIT DMG
>
HP%

Recommended Endgame Stats for Cyrene

HP
5000+
SPD
180+
CRIT Rate
50%
CRIT DMG
160%+

Traces Priority

Skills Priority
Memosprite Skill > Skill > Ultimate > Talent > Memosprite > Basic Attack
Major Traces Priority
Causality in Trichotomy > Ripples Across Time > Child of Remembrance

Cyrene's Best Teams

To learn all about Cyrene's synergies and best team compositions, check our dedicated Cyrene's team page below:

Saeldur
Staff Author
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This guide was written by Saeldur, expert Honkai: Star Rail theorycrafter and guide writer for Icy Veins. Saeldur is a high-end HSR player with a deep understanding of the various characters while also clearing PF, MoC and AS when each cycle releases.