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  • May 07, 2019 - Created.
  • August 20, 2019 - Added Qhira.

As a Ana enthusiast (she pratically became my main over Auriel, specially after the rework), I absolutely love trying out combos with Nano BoostNano Boost. In a similar fashion to my Auriel's Best Hope Bearers topic, this list aims to rank my personal experiences with Nano Boost (as well Nano InfusionNano Infusion) and the best Heroes to use it with.

Heroes that already have some sort of cooldown-reduction talent will often work wonders with Nano Boost, as their effects stack.

This guide will be updated constantly as new Heroes are launched and/or existing Heroes are reworked in a way that affects their DPS.

  1. Cho'gall: unsurprisingly, Cho'gall is arguably the best candidate for Nano Boost as it affects both Cho AND Gall, meaning they can use their already low cooldown abilities much faster, and with greater impact. Under the effects of Nano InfusionNano Infusion, Cho'gall is pratically unkillable, specially if Gall has picked Shadow Bolt VolleyShadow Bolt Volley with the ShadowfuryShadowfury upgrade, resulting in a massive self-sustain.
  2. Malthael: given Soul RipSoul Rip's very low cooldown, Malthael can madly spam it while under the effects of Nano BoostNano Boost, melting everything. He can become pratically unkillable by using Tormented SoulsTormented Souls (with Reaper of SoulsReaper of Souls) combined with Nano InfusionNano Infusion, with an uptime almost matching Nano Boost itself (even more if he manages to kill Heroes while under it, thus resetting the duration).
  3. Alarak: low cooldowns and obscene damage output with high stacks of SadismSadism makes Alarak a fantastic candidate for Nano BoostNano Boost, allowing him to deal eye-watering damage.
  4. Jaina: can annihilate the entire enemy team with Nano Boost in mere seconds, specially when combined with Icy VeinsIcy Veins and Ring of FrostRing of Frost.
  5. Chromie: with Nano BoostNano Boost, Chromie can destroy even high health tanks with her combo combining Temporal LoopTemporal Loop and Blessing of the BronzeBlessing of the Bronze, allowing her the to achieve the highest cooldown-reduction rate in the entire game.
  6. Kael'thas: in a similar fashion to Jaina, he can deal nasty damage with Nano BoostNano Boost, particularly with Living BombLiving BombPyroblastPyroblast can one-shot low health Heroes while Nano Boosted.
  7. Kel'Thuzad: can one-shot most enemies with his combo when Nano Boosted. If the conditions are right, he can use his combo up to two times before Nano Boost ends.
  8. Sonya: has a lot of potential under Wrath of the BerserkerWrath of the Berserker, which, combined with Nano BoostNano Boost AND Nano InfusionNano Infusion, can make her more destructive than Malthael. However, Sonya requires to be really close to deal damage consistently, and unfortunately she can be kited easily, which is why she ranked lower than Malthael.
  9. Sylvanas: after her rework, Sylvanas became a deadly mid-range Assassin that can deal surprisingly high burst damage with the proper build, making her a fantastic candidate for Nano BoostNano Boost.
  10. Genji: even after the nerfs to this combo a long time ago, it still is a very powerful one, assuming Genji has enough crowd-control by his side to make the fullest of DragonbladeDragonblade.
  11. Greymane: can deal massive damage regardless of his build. Nano InfusionNano Infusion also provides Greymane with very needed self-sustain, which is his greatest weakness.
  12. Gul'dan: can spam Fel FlameFel Flame like crazy under the effects of Nano BoostNano Boost. If the circumstances are right, he can use CorruptionCorruption up to three times or more before Nano Boost ends; assuming Bound by ShadowBound by Shadow is taken and he hits as many enemies as possible with Fel Flame.
  13. Valla: being a hybrid of basic attacker and spell damage dealer, she can deal surprisingly high damage under the effects of Nano BoostNano Boost regardless of her build, although her Hungering ArrowHungering Arrow can be relatively easy to avoid.
  14. Cassia: can make a mess with Nano BoostNano Boost regardless of her build, although she is particularly more effective with the Lightning FuryLightning Fury build with Ball LightningBall Lightning.
  15. Zeratul: absurdly high burst that becomes even more insane under the effects of Nano BoostNano Boost. Not ranked as high as other Assassins because he requires a LOT of skill to make the fully use of Nano Boost.
  16. Li-Ming: innate cooldown resets upon takedowns combined with already low cooldowns makes Li-Ming a beast under the effects of Nano BoostNano Boost. If the circumstances are right, she can spam her abilities like crazy. However, her skillshots are relatively easy to avoid.
  17. Mephisto: innate cooldown reduction on his abilities due to his trait, Lord Of HatredLord Of Hatred, makes him a fantastic candidate to Nano BoostNano Boost. However, much like Li-Ming, he is ranked lower than the other "mages" because he can not guarantee to get many resets in succession. On the other hand, Consume SoulsConsume Souls (with Consumed by HatredConsumed by Hatred) can potentially wipe the entire enemy team.
  18. Orphea: quick resets on Shadow WaltzShadow Waltz combined with strong sustained damage makes her a good candidate for Nano BoostNano Boost, however she falls in a similar category as Li-Ming, since her skillshots are relatively easy to avoid; plus she is a mid-range "mage", which makes approaches harder.
  19. Qhira: can deal a huge burst damage with Blood RageBlood Rage and either Heroic Ability, making her a viable candidate for Nano BoostNano Boost.
  20. Azmodan: when fully stacked, Azmodan can decimate the entire enemy team with a Black PoolBlack Pool-infused Globe of AnnihilationGlobe of Annihilation while under the effects of Nano BoostNano Boost. He is not ranked so high, however, because his cooldowns are very long, resulting on him not making full potential of the 8 second duration of Nano Boost, even with 150% recharge rate.
  21. Kerrigan: in a similar fashion to Greymane, can deal massive damage in seconds, and Nano InfusionNano Infusion makes her even more durable. However, she is ranked lower than him because her combo requires proper setup to work.
  22. Thrall: he falls in a similar category as Sonya, as he can deal a lot of damage but can be relatively easy to kite, making his usefulness under Nano BoostNano Boost not the best one, but still very powerful, specially with the Chain LightningChain Lightning build.
  23. Junkrat: with the Frag LauncherFrag Launcher build, Junkrat can deal A LOT of damage when Nano Boosted. He is ranked low, however, because his grenades are easy to avoid. On the other hand, RIP-TireRIP-Tire can really make a mess.
  24. Ragnaros: much like Kerrigan and Sonya, he must be really close to deal proper damage, but can deal a lot if given the chance, making him a potential candidate for Nano BoostNano Boost. He cannot be Nano Boosted while on Molten CoreMolten Core, and will not retain its effects if he gets Nano Boost and then activates Molten Core.
  25. Zul'jin: with the Twin CleaveTwin Cleave + GuillotineGuillotine build, he can deal a LOT of damage in quickly succession. However, given the high cooldowns of both abilities, as well the condition of requiring lower health to deal maximum damage with Guillotine, he doesn't work as good under Nano BoostNano Boost compared to other characters.
  26. Maiev: while she has a lot of potential under the effects of Nano BoostNano Boost because of her Fan of KnivesFan of Knives resets, she needs to hit at least two Heroes with it, making the combo more situational.
  27. Fenix: while being mostly a basic attacker, he can deal surprisingly high damage with Plasma CutterPlasma Cutter, and both his Heroic abilities become even more dangerous with Nano BoostNano Boost.
  28. Murky: can become ridiculously hard to kill with the SlimeSlime build + Living the DreamLiving the Dream + Fish TankFish Tank. Combine that with Nano InfusionNano Infusion, and the murloc can go on a rampage! Not ranked so high because of his low health.
Edited by Valhalen
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nano jaina is 👌 its so much fun if you pop icy veins at the same time, you just walk through enemy teams

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44 minutes ago, Blainie said:

nano jaina is 👌 its so much fun if you pop icy veins at the same time, you just walk through enemy teams

I'm actually considering on ranking her above Alarak, but from many tests I've seen Alaraks obliterating entire enemy teams with Lightning Surge spams. On the other hand, Jaina packs way more punch if the conditions are right. So it is really hard to measure.

Edited by Valhalen

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1 hour ago, Valhalen said:

I'm actually considering on ranking her above Alarak, but from many tests I've seen Alaraks obliterating entire enemy teams with Lightning Surge spams. On the other hand, Jaina packs way more punch if the conditions are right. So it is really hard to measure.

If the Blizzard and Cone land at the right time, especially at above level 20 with Water Ele duplicate spells, it's just like a bomb going off. I'd say their ranking depends on the point in the game and what level the teams are at.

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17 minutes ago, Blainie said:

If the Blizzard and Cone land at the right time, especially at above level 20 with Water Ele duplicate spells, it's just like a bomb going off. I'd say their ranking depends on the point in the game and what level the teams are at.

Yeah. I'm ranking characters based on overall performance, but it is trickier than that. Too many variables; for instance, are summons affected by Nano BoostNano Boost, such as the aforementioned Summon Water ElementalSummon Water Elemental? Still, I suppose it is a good parameter, nevertheless. Will run more tests in the future.

Resultado de imagem para mordin solus

Edited by Valhalen

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