Welcome to our Talents page for Ana. Here, we give you an overview of how strong each of Ana's talents is. Then, we present several viable builds, before analyzing each talent row separately, so that you can make informed decisions.
Ana's Talent Build
|1||? ✓ ✘︎|
|4||? ✓ ?|
|7||? ✓ ?|
|13||? ? ✓|
|16||? ? ✓|
|20||✓ ? ? ?|
Ana's Talent Build Cheatsheet
Sleep Dart BuildRecommended
Ana's Sleep Dart Build is designed to compensate the Slow provided by the Aim Down Sights effect included in Shrike by giving Ana some Movement Speed and by Slowing enemy Heroes, using Night Terrors and Slumber Shells respectively; furthermore, the former Talent adds burst damage in the form of Percent Damage.
Level 1 Talents for Ana
Hitting Heroes with Biotic Grenade increases its damage and healing by 30% per Hero hit.
Contact Healing is a good Talent during team fights with several Heroes—regardless of them being friends or foes—clumping next to each other.
You can use this Talent as a survivability tool against dive because of the extra healing and/or to punish multiple enemy Heroes at the same time because of the extra damage.
Reduce the cooldown of Sleep Dart by 2 seconds. Upon waking, enemy Heroes are Slowed by 25% for 3 seconds.
The relatively small Slow provided is enough to annoy enemy Heroes that are trying to reposition, especially if they lack mobility, and allied Heroes that are trying to damage them, especially if they rely on Basic Attacks.
The cooldown reduction has synergy with Night Terrors at Level 7 because it allows you to get value from that Talent more often.
Quest: Stack 5 Doses on an enemy Hero or Basic Attack a Hero with 5 Doses.
Reward: Stack 5 Doses to increase Shrike's healing by 1%.
Reward: Basic Attack a Hero with 5 Doses to increase Shrike's healing by 0.25%.
We do not recommend this Talent because you can increase your own survivability by going for Contact Healing instead, a Talent that does not require you to unnecessarily expose to farm a Quest that is supposed to make you a bit harder to kill.
Level 4 Talents for Ana
Increase the bonus healing duration of Biotic Grenade by 50% and reduce its cooldown by 3 seconds.
The small cooldown reduction provided by this Talent is not really useful considering that you mostly want to hold Biotic Grenade for the perfect moment in order to reduce as much enemy healing as possible or to save an allied Hero who is suddenly in trouble.
The increased bonus healing duration works only when you use Biotic Grenade in a defensive way and perfectly time it to empower an additional Healing Dart than usual.
Sleep Dart applies 4 Doses. While Aim Down Sights is active, Sleep Dart pierces all enemy Heroes.
While they not look that powerful, when you do not have time or space to use Basic Attacks, the 4 Doses indirectly increase by 176 the damage done with Sleep Dart.
The infinite pierce is useful when you want to ensure that Sleep Dart connects on the enemy backline (for example when you want to interrupt Holy Word: Salvation even if more than one enemy Hero is between Ana and Anduin).
- Cooldown: 20 seconds
Fire a dart which Slows the Movement Speed and reduces the damage dealt by the first enemy Hero it hits by 50% for 4 seconds. If no Heroes are hit, reduce this cooldown by 8 seconds.
Debilitating Dart is a situational Talent that gives Ana what she needs the most: self-peeling. If you hit an enemy Hero with it, they will be Slowed by 50% and deal 50% less damage for 4 seconds. If you miss enemy Heroes, you will get 8 seconds of cooldown reduction.
- When you want to increase your chance to connect Sleep Dart, try hitting the enemy Hero with Debilitating Dart first because the Slow provided will help with that.
- When you want to increase your chances to connect Debilitating Dart will hit, try hitting the enemy Hero with Sleep Dart first because the Sleep will help with that.
In short, use first what you need less and, whether you hit or miss, follow-up with what you need more.
Level 7 Talents for Ana
Increase the area of Biotic Grenade by 25% and the duration of the healing reduction by 0.75 seconds.
The increased healing reduction duration is not really needed because a well-timed Biotic Grenade lasts enough to deny the most powerful healing Abilities used on the focused enemy Hero by themselves or their team.
Gain 25% Movement Speed for 2 seconds for every Hero hit by Sleep Dart. Upon waking, enemy Heroes take 8% of their Maximum Health in damage.
Night Terrors is a strong Talent that provides both a fair amount of mobility, something that Ana lacks, and a high amount of burst damage, something that is extremely powerful when combined with the healing reduction provided by Biotic Grenade indirectly acts as burst damage.
The bonus damage will trigger either when the Sleep lasts for its full duration or when it ends pre-emptively. The damage part is particularly effective on high-Health enemy Heroes, usually Tanks and Bruisers.
The bonus Movement Speed is really good to save Ana from trouble when she has Shrike active and cannot disable it yet due to the 4 seconds cooldown not allowing because it will basically make you move at normal Movement Speed 2 seconds earlier than usual.
Every Dose a Hero has reduces their Spell Power by 10%.
Mind-Numbing Agent is a decent Talent that allows Ana to reduce both damage and healing coming from enemy Abilities used by the target of her Basic Attacks.
Level 10 Talents for Ana
In this section we discuss when and why to pick a given Heroic Ability. If you want to read how they work and/or you are looking for some tips on how to use them, check the dedicated section in the Abilities and Strategy page.
- Mana: 60
- Cooldown: 70 seconds
Instantly boost an allied Hero, restoring 200 Mana. For the next 8 seconds, they gain 30% Spell Power and their Basic Ability cooldowns recharge 150% faster.
Cannot be used on Ana.
- Mana: 45
- Cooldown: 60 seconds
Assume a sniping position, gaining the ability to fire up to 6 specialized rounds with unlimited range. Rounds pierce allied and enemy Heroes but collide with enemy Structures in their path. Allies are healed for 225 (+4% per level) and enemies are damaged for 135 (+4% per level). Deals 50% less damage to Structures.
Ana is unable to move while Eye of Horus is active.
Level 13 Talents for Ana
Healing Dart grants 25% Movement Speed to affected Heroes for 1 seconds.
While it is not a big deal, you should know that the Movement Speed provided by this Talent can also potentially mess up your aim because the Movement Speed buff will expire exactly when the next Healing Dart will come off cooldown.
Healing Dart removes Roots and Slows from the target, and heals for 20% more when doing so.
Healing Dart removes Stuns from the target, and grants them 50 Armor for 2 seconds when doing so.
Pick this Talent every time you play against a team who has at least a Stun and some burst damage to get value out of it because even having 50 Armor for 2 seconds only once per team fight is a big survivability boost.
Level 16 Talents for Ana
Healing Dart's healing is increased by 5% if it heals a Hero, up to 50%. At maximum bonus, further increase its healing by 35%. This bonus is reset if Healing Dart fails to hit a Hero.
Sharpshooter is a decent Talent that greatly increases the amount healed by Healing Dart if you hit allied Heroes multiple times in a row. You can use this Talent in combat and out of combat because it does not require enemy Heroes to work.
The main problem with this Talent is that occasionally missing allied Heroes with Healing Dart will cause you to lose a lot of its value, altough it may be useful to heal up allied Heroes which are quite easy to hit thanks to their big hitbox and lack of mobility (such as Azmodan).
Increase Healing Dart's healing by 12% for each Dose active on enemy Heroes.
Concentrated Doses is a good Talent that increases the amount healed by Healing Dart based on the number of Doses you have applied on enemy Heroes via Shrike. You can use this Talent in combat but not out of combat because it requires enemy Heroes to work.
Activate to instantly gain 3 charges of Healing Dart.
Active Reload is a strong Talent that gives Ana a huge amount of burst healing when needed. It comes with a reasonable cooldown of 60 seconds, allowing Ana to have it available for every important team fight.
The most interesting part about this Talent is that it makes up for occasionally missing Healing Dart, so it slightly reduces the chances you will lose a team fight for a single miss.
Level 20 Talents for Ana
Allies affected by Nano Boost heal for 50% of Spell Damage dealt.
The additional healing it provides can help the target allied Hero to go for a more aggressive playstyle to deliver as many empowered Abilities as possible.
Increase Eye Of Horus' healing and damage by 5% for every Hero hit. This bonus resets after all shots have been fired.
Deadeye is a good Talent that empowers Eye of Horus each time it hits an allied or enemy Hero. If the enemy team composition tends to play grouped, it will easily ramp up in value because hitting multiple Heroes with a single shot will count as a multiple hits.
Increase Shrike's damage by 50%. While Aim Down Sights is active, gain 25 Armor.
Armored Stance is a situational Talent that, other than slightly increasing her damage done by around 20%, gives Ana more survivability in the form of Armor and self-sustain derived from the additional Shrike's damage being partially converted to healing.
Basic Attacks increase Attack Speed by 10% for 3 seconds, up to 100%. While Aim Down Sights is active, increase your Basic Attack Range by 4.
Dynamic Optics is a situational Talent that gives Ana 50% more damage per second by increasing her Attack Speed, something that will also increase her self-sustain thanks to Shrike converting part of the damage to healing.
- 28 Sep. 2021: Guide reviewed for the latest Balance Update.
- 08 Oct. 2020: Guide reviewed for the latest Balance Update.
- 12 Aug. 2020: Talent Build page updated.
- Build added.
- Minor fixes.
- New layout.
- 22 Apr. 2020: Talent Build Cheatsheet updated to reflect the current metagame.
- 31 Mar. 2020: Talent Build fully revised to match new standards.
- Talent Build and Talent Build Cheatsheet modified to reflect the current metagame.
- Talent Descriptions modified to better describe when to pick them.
- 03 Jun. 2019: Changed Eye of Horus from Situational to Recommended and updated the talent builds accordingly.
- 13 Feb. 2019: Updated Ana's talents and builds in accordance with the latest rework.
- 07 Mar. 2018: Updated Ana's Talent Builds in accordance with the most recent balanced update.
- 29 Jan. 2018: Overdose is now Recommended and Aim Down Sights is now Not Recommended as intended.
- 13 Oct. 2017: Changed Dynamic Shooting from Not Recommended to Recommended and fixed Overdose's description.
- 29 Sep. 2017: Updated talent builds and descriptions after further playtesting.
- 28 Sep. 2017: Added talent discussions.
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