Ana Talents

Last updated on Oct 08, 2020 at 08:00 by Elitesparkle 39 comments
General Information

Welcome to our Talents page for Ana. Here, we give you an overview of how strong each of Ana's talents is. Then, we present several viable builds, before analyzing each talent row separately, so that you can make informed decisions.

1.

Ana's Talent Build

Level Choices
1 Contact Healing ? Slumber Shells Vampiric Rounds ✘︎
4 Biotic Enhancements ? Overdose Debilitating Dart ?
7 Anti-Healer ? Night Terrors Mind-Numbing Agent ?
10 Nano Boost Eye of Horus ?
13 Speed Serum ? Purifying Darts ? Smelling Salts
16 Sharpshooter ✘︎ Concentrated Doses ✘︎ Active Reload
20 Nano Infusion Deadeye ? Armored Stance ? Dynamic Optics ?
2.

Ana's Talent Build Cheatsheet

Sleep Dart Build

Recommended
Level 1 Slumber Shells Icon
Level 4 Overdose Icon Debilitating Dart Icon ?
Level 7 Night Terrors Icon
Level 10 Nano Boost Icon
Level 13 Smelling Salts Icon Purifying Darts Icon ?
Level 16 Active Reload Icon
Level 20 Nano Infusion Icon

Ana's Sleep Dart Build is designed to compensate the Slow provided by the Aim Down Sights effect included in Shrike Icon Shrike by giving Ana some Movement Speed and by Slowing enemy Heroes, using Night Terrors Icon Night Terrors and Slumber Shells Icon Slumber Shells respectively; furthermore, the former Talent adds burst damage in the form of Percent Damage.

Biotic Grenade Build

Beginner
Level 1 Contact Healing Icon
Level 4 Biotic Enhancements Icon Debilitating Dart Icon ?
Level 7 Anti-Healer Icon
Level 10 Nano Boost Icon
Level 13 Smelling Salts Icon Purifying Darts Icon ?
Level 16 Active Reload Icon
Level 20 Nano Infusion Icon

Ana's Biotic Grenade Build is all about healing allied Heroes and yourself, with Contact Healing Icon Contact Healing increasing her survivability and Anti-Healer Icon Anti-Healer making it better and easier to use.

3.

Level 1 Talents for Ana

Ana Contact Healing ?
Contact Healing (Level 1) Ana

Biotic Grenade heals for 30% more per allied and enemy Hero hit.

Contact Healing Icon Contact Healing is a good Talent during team fights with several Heroes—regardless of them being friends or foes—clumping next to each other, but it is mostly used as a survivability tool against dive.

Even if not that much, Contact Healing Icon Contact Healing benefits from Biotic Enhancements Icon Biotic Enhancements at Level 4 because of the cooldown reduction.

Ana Slumber Shells
Slumber Shells (Level 1) Ana

Reduce the cooldown of Sleep Dart by 2 seconds. Upon waking, enemy Heroes are Slowed by 25% for 3 seconds.

Slumber Shells Icon Slumber Shells is a strong Talent that slightly improves Sleep Dart Icon Sleep Dart by making it Slowing enemy Heroes right after the Sleep ends and by slightly reducing its cooldown.

The relatively small Slow provided is enough to annoy enemy Heroes that are trying to reposition, especially if they lack mobility, and allied Heroes that are trying to damage them, especially if they rely on Basic Attacks.

The cooldown reduction has synergy with Night Terrors Icon Night Terrors at Level 7 because it allows you to get value from that Talent more often.

Ana Vampiric Rounds
Vampiric Rounds (Level 1) Ana

Quest: Stack 5 Doses on an enemy Hero or Basic Attack a Hero with 5 Doses.

Reward: Stack 5 Doses to increase Shrike's healing by 0.25%.

Reward: Basic Attack a Hero with 5 Doses to increase Shrike's healing by 0.25%.

Vampiric Rounds Icon Vampiric Rounds is a weak Quest-based Talent that provides self-sustain tied to Basic Attacks.

We do not recommend this Talent because you can increase your own survivability by going for Contact Healing Icon Contact Healing instead, a Talent that does not require you to unnecessarily expose to farm a Quest that is supposed to make you a bit harder to kill.

4.

Level 4 Talents for Ana

Ana Biotic Enhancements ?
Biotic Enhancements (Level 4) Ana

Increase the bonus healing duration of Biotic Grenade by 50% and reduce its cooldown by 2 seconds.

Biotic Enhancements Icon Biotic Enhancements is a decent Talent that causes Biotic Grenade Icon Biotic Grenade to have a slightly lower cooldown and a bit higher uptime on the healing increase effect.

The small cooldown reduction provided by this Talent is not really useful considering that you mostly want to hold Biotic Grenade Icon Biotic Grenade for the perfect moment in order to reduce as much enemy healing as possible or to save an allied Hero who is suddenly in trouble.

The increased bonus healing duration works only when you use Biotic Grenade in a defensive way and perfectly time it to empower an additional Healing Dart Icon Healing Dart than usual.

All that said, thanks to the cooldown reduction provided, Biotic Enhancements Icon Biotic Enhancements has synergy with Biotic Grenade Icon Biotic Grenade-based Talents: Contact Healing Icon Contact Healing at Level 1 and Anti-Healer Icon Anti-Healer at Level 7. It should be picked only alongside these Talents, however, it is not mandatory.

Ana Overdose
Overdose (Level 4) Ana

Sleep Dart applies 4 Doses. While Aim Down Sights is active, Sleep Dart pierces all enemy Heroes.

Overdose Icon Overdose is a strong Talent that makes Sleep Dart Icon Sleep Dart apply 4 Doses of Shrike Icon Shrike to any enemy Hero hit and makes it pierce any number of enemy Heroes.

While they not look that powerful, when you do not have time or space to use Basic Attacks, the 4 Doses indirectly increase by 176 the damage done with Sleep Dart Icon Sleep Dart.

The infinite pierce is useful when you want to ensure that Sleep Dart Icon Sleep Dart connects on the enemy backline (for example when you want to interrupt Holy Word: Salvation Icon Holy Word: Salvation even if more than one enemy Hero is between Ana and Anduin).

Ana Debilitating Dart ?
Debilitating Dart (Level 4) Ana
  • Cooldown: 20 seconds

Activate to fire a dart which Slows the Movement Speed and reduces the damage dealt by the first enemy Hero it hits by 50% for 4 seconds.

Debilitating Dart Icon Debilitating Dart is a situational Talent that gives Ana what she needs the most: self-peeling. If you hit an enemy Hero with it, they will be Slowed by 50% and deal 50% less damage for 4 seconds.

Other than being usable on its own or as a follow-up to allied crowd control, this additional Active Ability with 20 seconds of cooldown can be used either before or after Sleep Dart Icon Sleep Dart:

  • When you want to increase your chance to connect Sleep Dart, try hitting the enemy Hero with Debilitating Dart first because the Slow provided will help with that.
  • When you want to increase your chances to connect Debilitating Dart Icon Debilitating Dart will hit, try hitting the enemy Hero with Sleep Dart Icon Sleep Dart first because the Sleep will help with that.

In short, use first what you need less and, whether you hit or miss, follow-up with what you need more.

5.

Level 7 Talents for Ana

Ana Anti-Healer ?
Anti-Healer (Level 7) Ana

Increase the area of Biotic Grenade by 25% and the duration of the healing reduction by 0.75 seconds.

Anti-Healer Icon Anti-Healer is a decent Talent that provides a bit more uptime on the healing reduction by itself and, more importantly, increases the area covered by Biotic Grenade Icon Biotic Grenade.

The increased healing reduction duration is not really needed because a well-timed Biotic Grenade Icon Biotic Grenade lasts enough to deny the most powerful healing Abilities used on the focused enemy Hero by themselves or their team.

The area extension has synergy with Contact Healing Icon Contact Healing at Level 1, resulting in more healing and self-sustain.

Even if not that much, Anti-Healer Icon Anti-Healer benefits from Biotic Enhancements Icon Biotic Enhancements at Level 4 because of the cooldown reduction.

Ana Night Terrors
Night Terrors (Level 7) Ana

Gain 25% Movement Speed for 2 seconds for every Hero hit by Sleep Dart. Upon waking, enemy Heroes take 8% of their Maximum Health in damage.

Night Terrors Icon Night Terrors is a strong Talent that provides both a fair amount of mobility, something that Ana lacks, and a high amount of burst damage, something that is extremely powerful when combined with the healing reduction provided by Biotic Grenade Icon Biotic Grenade indirectly acts as burst damage.

The bonus damage will trigger either when the Sleep lasts for its full duration or when it ends pre-emptively. The damage part is particularly effective on high-Health enemy Heroes, usually Tanks and Bruisers.

The bonus Movement Speed is really good to save Ana from trouble when she has Shrike Icon Shrike active and cannot disable it yet due to the 4 seconds cooldown not allowing because it will basically make you move at normal Movement Speed 2 seconds earlier than usual.

Ana Mind-Numbing Agent ?
Mind-Numbing Agent (Level 7) Ana

Every Dose a Hero has reduces their Spell Power by 10%.

Mind-Numbing Agent Icon Mind-Numbing Agent is a decent Talent that allows Ana to reduce both damage and healing coming from enemy Abilities used by the target of her Basic Attacks.

Pick this Talent when you want to nerf the enemy the enemy Tank or Bruiser. Do not see this Talent as a counter to Mages because you cannot reliably use Basic Attacks on them.

6.

Level 10 Talents for Ana

In this section we discuss when and why to pick a given Heroic Ability. If you want to read how they work and/or you are looking for some tips on how to use them, check the dedicated section in the Abilities and Strategy page.

Ana Nano Boost
Nano Boost (Level 10) Ana
  • Mana: 60
  • Cooldown: 70 seconds

Instantly boost an allied Hero, restoring 200 Mana. For the next 8 seconds, they gain 30% Spell Power and their Basic Ability cooldowns recharge 150% faster.

Cannot be used on Ana.

Nano Boost Icon Nano Boost is a strong Heroic Ability when your team features a Mage (such as Kel'Thuzad or even Alarak) that can benefit from both Spell Power and cooldown reduction.

Ana Eye of Horus ?
Eye of Horus (Level 10) Ana
  • Mana: 45
  • Cooldown: 60 seconds

Assume a sniping position, gaining the ability to fire up to 6 specialized rounds with unlimited range. Rounds pierce allied and enemy Heroes but collide with enemy Structures in their path. Allies are healed for 225 (+4% per level) and enemies are damaged for 135 (+4% per level). Deals 50% less damage to Structures.

Ana is unable to move while Eye of Horus is active.

Eye of Horus Icon Eye of Horus is a situational Heroic Ability that can be useful on Maps where it is crucial to win the solo lane and you want a tool to help with that.

7.

Level 13 Talents for Ana

Ana Speed Serum ?
Speed Serum (Level 13) Ana

Healing Dart grants 25% Movement Speed to affected Heroes for 1 seconds.

Speed Serum Icon Speed Serum is a situational Talent that can be used to enable aggressive plays on low-mobility Heroes (for example Garrosh).

While it is not a big deal, you should know that the Movement Speed provided by this Talent can also potentially mess up your aim because the Movement Speed buff will expire exactly when the next Healing Dart Icon Healing Dart will come off cooldown.

Ana Purifying Darts ?
Purifying Darts (Level 13) Ana

Healing Dart removes Roots and Slows from the target, and heals for 20% more when doing so.

Purifying Darts Icon Purifying Darts is a good Talent to increase your sustain healing because Slows are really common and it also works against Roots.

Pick this Talent when you cannot get enough value from Smelling Salts Icon Smelling Salts or when you really need to remove a Root to save allied Heroes from death (such as against Kel'Thuzad).

Ana Smelling Salts
Smelling Salts (Level 13) Ana

Healing Dart removes Stuns from the target, and grants them 50 Armor for 2 seconds when doing so.

Smelling Salts Icon Smelling Salts is a strong Talent that gets massive value against burst compositions, teams whose main strategy is to Stun an enemy Hero and then follow-up with burst damage.

Pick this Talent every time you play against a team who has at least a Stun and some burst damage to get value out of it because even having 50 Armor for 2 seconds only once per team fight is a big survivability boost.

8.

Level 16 Talents for Ana

Ana Sharpshooter
Sharpshooter (Level 16) Ana

Healing Dart's healing is increased by 5% if it heals a Hero, up to 50%. This bonus is reset if Healing Dart fails to hit a Hero.

Sharpshooter Icon Sharpshooter is a decent Talent that increases your already good sustained healing in and out of combat even more, yet it does not compete with the utility provided by Active Reload Icon Active Reload explained later on.

Ana Concentrated Doses
Concentrated Doses (Level 16) Ana

Increase Healing Dart's healing by 10% for each Dose active on enemy Heroes.

Concentrated Doses Icon Concentrated Doses is a weak Talent that increases your already good sustained healing in combat but not out of combat, yet it does not match the value given by Active Reload Icon Active Reload mentioned below.

Being based on the number of Doses active on enemy Heroes, this Talent has synergy with Overdose Icon Overdose at Level 4.

Ana Active Reload
Active Reload (Level 16) Ana

Activate to instantly gain 3 charges of Healing Dart.

Active Reload Icon Active Reload is a strong Talent that gives Ana a huge amount of burst healing when needed. It comes with a reasonable cooldown of 60 seconds, allowing Ana to have it available for every important team fight.

9.

Level 20 Talents for Ana

Ana Nano Infusion
Nano Infusion (Level 20) Ana

Allies affected by Nano Boost heal for 50% of Spell Damage dealt.

Nano Infusion Icon Nano Infusion is a strong Talent with no downsides that increases the survivability of whoever you target with Nano Boost Icon Nano Boost based on the amount of Spell Damage they can deal.

The additional healing it provides can help the target allied Hero to go for a more aggressive playstyle to deliver as many empowered Abilities as possible.

Ana Deadeye ?
Deadeye (Level 20) Ana

Increase Eye Of Horus' healing and damage by 4% for every Hero hit. This bonus resets after all shots have been fired.

Deadeye Icon Deadeye is a good Talent that empowers Eye of Horus Icon Eye of Horus each time it hits an allied or enemy Hero.

The additional damage and healing it gives can allow you to secure a kill or to save an allied Hero respectively.

If the enemy team composition tends to play grouped, it will easily ramp up in value because hitting multiple Heroes with a single shot will count as a multiple hits.

Ana Armored Stance ?
Armored Stance (Level 20) Ana

Increase Shrike's damage by 50%. While Aim Down Sights is active, gain 25 Armor.

Armored Stance Icon Armored Stance is a situational Talent that, other than slightly increasing her damage done by around 20%, gives Ana more survivability in the form of Armor and self-sustain derived from the additional Shrike Icon Shrike's damage being partially converted to healing.

Ana Dynamic Optics ?
Dynamic Optics (Level 20) Ana

Basic Attacks increase Attack Speed by 10% for 3 seconds, up to 100%. While Aim Down Sights is active, increase your Basic Attack Range by 4.

Dynamic Optics Icon Dynamic Optics is a situational Talent that gives Ana 50% more damage per second by increasing her Attack Speed, something that will also increase her self-sustain thanks to Shrike Icon Shrike converting part of the damage to healing.

10.

Changelog

  • 08 Oct. 2020: Guide reviewed for the latest Balance Update.
  • 12 Aug. 2020: Talent Build page updated.
    • Build added.
    • Minor fixes.
    • New layout.
  • 22 Apr. 2020: Talent Build Cheatsheet updated to reflect the current metagame.
  • 31 Mar. 2020: Talent Build fully revised to match new standards.
    • Talent Build and Talent Build Cheatsheet modified to reflect the current metagame.
    • Talent Descriptions modified to better describe when to pick them.
  • 03 Jun. 2019: Changed Eye of Horus from Situational to Recommended and updated the talent builds accordingly.
  • 13 Feb. 2019: Updated Ana's talents and builds in accordance with the latest rework.
  • 07 Mar. 2018: Updated Ana's Talent Builds in accordance with the most recent balanced update.
  • 29 Jan. 2018: Overdose is now Recommended and Aim Down Sights is now Not Recommended as intended.
  • 13 Oct. 2017: Changed Dynamic Shooting from Not Recommended to Recommended and fixed Overdose's description.
  • 29 Sep. 2017: Updated talent builds and descriptions after further playtesting.
  • 28 Sep. 2017: Added talent discussions.
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