Welcome to our Talents page for Ana. Here, we give you an overview of how strong each of Ana's talents is. Then, we present several viable builds, before analyzing each talent row separately, so that you can make informed decisions.
1. Ana's Talent Build
|1||✔ ✔ ✘|
|4||✔ ✘ ✔|
|7||? ✔ ✔|
|13||? ? ?|
|16||✘ ✔ ✔|
|20||✘ ✘ ✔ ✔ ✘|
2. Ana's Talent Build Cheatsheet
All-round BuildTalent calculator »
The All-round Build comes with a lot of utility and provides, as the name suggests, solid value in most games. However, it is very important to carefully analyze the enemy team composition in terms of crowd control and damage type. If the opposing roster features strong ability damage dependent Assassins, Mind-Numbing Agent at Level 7 can be a strong choice to lower their combat efficiency. Similarly, Speed Serum at Level 13 can be replaced by Purifying Darts or Smelling Salts depending on what form of crowd control the enemy team relies on the most.
Grenade BuildTalent calculator »
The Grenade Build provides strong AoE healing, which is particularly good if your team has several melee Heroes who usually clump next to each other. When playing Ana it is very important to carefully analyze the enemy team composition in terms of crowd control and damage type. Mind-Numbing Agent at Level 7 can be a strong choice against Mages, whereas Speed Serum at Level 13 can be replaced by Purifying Darts or Smelling Salts depending on what form of crowd control the enemy team relies on the most.
3. Level 1 Talents for Ana
Quest: Hit enemy Heroes with Biotic Grenade.
Reward: After hitting 10 Heroes, Biotic Grenade does 75% more damage per allied and enemy Hero hit.
Reward: After hitting 20 Heroes, Biotic Grenade's duration on allies is increased from 4 seconds to 12 seconds, its healing radius is increased by 100%, and its healing amplification applies to all sources.
Quest: Hit Heroes with Sleep Dart.
Reward: After hitting 10 Heroes, Sleep Dart now hits 2 Heroes and its range is increased by 25%.
Reward: After hitting 20 Heroes, Healing Dart now hits 2 Heroes and its range is increased by 25%.
Quest: Stack 5 Doses on an enemy Hero.
Reward: After reaching maximum Dosage 12 times, unlock the Active Reload Ability, which can be activated to instantly gain 3 charges of Healing Dart.
Grenade Calibration works very well with Heroes who are capable of using self-healing abilities, since they benefit heavily from the increased duration of the healing buff. The increased damage on enemies is a beautiful extra to have.
Piercing Darts seems weak at first glance, however, after successfully completing it, Ana's power level increases significantly. Being able to hit up to 2 Heroes instead of just 1 allows her to reach targets that would get body-blocked otherwise.
Detachable Box Magazine's reward is quite powerful, however, it usually takes too long to unlock the quest reward. As such, we found it to be underwhelming when compared to the other Level 1 talents.
4. Level 4 Talents for Ana
Hitting enemy Heroes with Sleep Dart applies 3 Doses.
- Cooldown: 3 seconds
Shrike can be activated to increase vision radius by 100% and Basic Attack range by 2 but reduce Movement Speed by 20%. Lasts until canceled.
- Mana: 50
- Cooldown: 12 seconds
Activate to use Biotic Grenade with a 275% increased range, but Grenades thrown this way take 3 seconds to land.
Passive: Reduce Biotic Grenade cooldown by 4 seconds.
Air Strike causes Biotic Grenade to have a lower cooldown, which is particularly useful if you go for a Grenade Build in the first place. The resulting synergy with talents like Grenade Calibration at Level 1 and Contact Healing at Level 16 turns Ana into a quite potent AoE healer.
Aim Down Sights's Movement Speed reduction of 20% is too much of a drawback to make this talent relevant, since Ana's overall mobility is already very limited.
5. Level 7 Talents for Ana
After Sleep Dart's effects wear off, targets are Blinded for 2 seconds.
Every Dose a Hero has reduces their Spell Power by 10%.
- Cooldown: 20 seconds
Activate to fire a dart which Slows the Movement Speed and reduces the damage dealt by the first enemy Hero it hits by 50% for 3 seconds.
Debilitating Dart is a fantastic defensive talent to keep Ana safe from engagin Assassins and Warriors who could pressure her otherwise. The 20-second cooldown is low enough to make this talent worth the pick.
Mind-Numbing Agent is a great talent if the enemy team features multiple Mages. But even without a lot of spell damage in their ranks, Numbing Agents will cripple enemy Heroes significantly. The best part about this talent is the fact that it gets applied passively, which makes it very reliable.
6. Level 10 Talents for Ana
- Mana: 60
- Cooldown: 70 seconds
Instantly boost an allied Hero, restoring 200 Mana. For the next 8 seconds, they gain 30% Spell Power and their Basic Ability cooldowns recharge 150% faster.
Cannot be used on Ana.
- Mana: 45
- Cooldown: 45 seconds
Assume a sniping position, gaining the ability to fire up to 6 specialized rounds with unlimited range. Rounds hit the first allied or enemy Hero or enemy Structure in their path. Allies are healed for 285 (+4% per level) and enemies are damaged for 166 (+4% per level). Deals 50% less damage to Structures.
Ana is unable to move while Eye of Horus is active.
Nano Boost is the ultimate weapon when your team features one or several ability damage heavy Assassins like Alarak, Kael'thas, or Kel'Thuzad in your roster. Since the ability comes with a relatively long duration of 8 seconds, make sure to cast it at the beginning of a team fight rather than keeping it for too long.
Eye of Horus is an interesting Heroic Ability since it allows Ana to heal allies and damage opponents from anywhere on the map. However, the global range comes with a major drawback: it forces Ana to temporarily take on a stationary position, rendering her vulnerable to any form of crowd control and damage.
7. Level 13 Talents for Ana
Healing Dart grants 25% Movement Speed to affected Heroes for 1 seconds.
Healing Dart removes Roots and Slows from the target, and heals for 20% more when doing so.
Healing Dart removes Stuns from the target, and grants them 50 Armor for 2 seconds when doing so.
Speed Serum is a great all-round talent. Increased Movement Speed is something every ally will find useful. As a rule of thumb, choose this talent if you are not entirely sure what to pick.
8. Level 16 Talents for Ana
Healing Dart's healing is increased by 5% if it heals a Hero, up to 50%. This bonus is reset if Healing Dart fails to hit a Hero.
Increase Healing Dart's healing by 10% for each Dose active on enemy Heroes.
Biotic Grenade heals for 30% more per allied and enemy Hero hit.
Contact Healing can be an incredibly powerful talent during team fights with several Heroes — regardless of friend or foe — clumping next to each other. We also recommend this talent over Concentrated Doses if the enemy team has plenty of AoE damage that requires immediate AoE counter healing.
9. Level 20 Talents for Ana
Allies affected by Nano Boost heal for 50% of Spell Damage dealt.
Eye of Horus rounds explode upon impacting a Hero, healing nearby allies for 300 (+4% per level) and dealing 150 (+4% per level) damage to nearby enemy Heroes.
Upon stacking 5 Doses, Heroes are put to Sleep for 2 seconds.
Basic Attacks increase Attack Speed by 10% for 4 seconds, up to 100%.
Increase the Aim Down Sights Basic Attack range bonus from 2 to 4.
Somnolent Doses has great synergy with Overdose at Level 4, which helps stacking up to 5 Doses tremendously. The ability to cause enemy Heroes to fall asleep can be huge in many ways. It is great to catch up to fleeing opponents, and by the same token it keeps pesky Assassins and Warriors at bay. We consider this talent to be the big winner at Level 20.
Ballistic Advantage's explosion radius is rather small and the extra healing or damage it causes is too little to make it worth the investment.
- 07 Mar. 2018: Updated Ana's Talent Builds in accordance with the most recent balanced update.
- 29 Jan. 2018: Overdose is now Recommended and Aim Down Sights is now Not Recommended as intended.
- 13 Oct. 2017: Changed Dynamic Shooting from Not Recommended to Recommended and fixed Overdose's description.
- 29 Sep. 2017: Updated talent builds and descriptions after further playtesting.
- 28 Sep. 2017: Added talent discussions.
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