Mephisto Talents

Last updated on Mar 07, 2021 at 03:08 by Outofmilk 28 comments
General Information

Welcome to our Talents page for Mephisto. Here, we give you an overview of how strong each of Mephisto's talents is. Then, we present several viable builds, before analyzing each talent row separately, so that you can make informed decisions.


Mephisto's Talent Build

Level Choices
1 Unyielding Power Furious Spark ? Malicious Intent ✘︎
4 Hateful Mending ✘︎ Static Barrier ? Spite
7 Ghastly Armor ? Frost Storm ? Trickery
10 Consume Souls ? Durance of Hate
13 Abhorred Skull Hysteria ? Shard of Hate ?
16 Lightning Reaction Static Field ? Animosity ✘︎
20 Consumed by Hatred ? Unspeakable Horror ? Mimic Shade Lord ✘︎

Mephisto's Talent Build Cheatsheet

Skull Missile Build

Level 1 Unyielding Power Icon
Level 4 Spite Icon
Level 7 Trickery Icon Ghastly Armor Icon ? Frost Storm Icon ?
Level 10 Durance of Hate Icon Consume Souls Icon ?
Level 13 Abhorred Skull Icon
Level 16 Lightning Reaction Icon
Level 20 Unspeakable Horror Icon Consumed by Hatred Icon ?

The Skull Missile build focuses on buffing up Mephisto's Skull Missile. Through the level 1 Quest, we get an extra charge of Skull Missile. Combination with the later Talents turns Mephisto into a Hero with strong burst capabilities. The core strength of the build shows up at level 16; should you have the level 1 quest completed, everytime you dive in and are able to land your abilities, you turn Mephisto into a Skull Missile machine-gun.

Standard Lightning Nova Build

Level 1 Furious Spark Icon
Level 4 Static Barrier Icon
Level 7 Trickery Icon Ghastly Armor Icon ? Frost Storm Icon ?
Level 10 Durance of Hate Icon
Level 13 Shard of Hate Icon
Level 16 Static Field Icon
Level 20 Mimic Icon

The Lightning Nova Icon Lightning Nova focuses heavily on sticking to your enemies with your Nova, rewarding you greatly for doing so. Frost Storm Icon Frost Storm makes it much easier to keep Lightning Nova applied to enemies for maximum damage, but any of the Level 7 options can be very useful depending on the team compositions. Shard of Hate Icon Shard of Hate helps out with reducing the basic ability cooldowns of Mephisto, allowing you to dive in more often with Shade of Mephisto Icon Shade of Mephisto. Static Field Icon Static Field greatly enhances the damage and effective area of Lightning Nova. Once Mephisto has Mimic Icon Mimic, it becomes possible for him to completely reset the cooldowns of Lightning Nova and Shade of Mephisto. At this point, his Health and Mana are the only things limiting his ability to keep two Lightning Novas active throughout a team fight.

ARAM Build

Level 1 Unyielding Power Icon
Level 4 Spite Icon
Level 7 Ghastly Armor Icon
Level 10 Consume Souls Icon
Level 13 Hysteria Icon
Level 16 Lightning Reaction Icon
Level 20 Consumed by Hatred Icon

The ARAM Build focuses on Skull Missile and Mephisto's Trait. This allows for massive poke opportunities and more frequent usage of his Heroic Ability.


Level 1 Talents for Mephisto

Mephisto Unyielding Power
Unyielding Power (Level 1) Diablo Mephisto

Quest: Hit Heroes with Skull Missile.

Reward: After hitting 20 Heroes, increase Skull Missile's damage by 100.

Reward: After hitting 40 Heroes, Skull Missile gains an additional charge.

Mephisto Furious Spark ?
Furious Spark (Level 1) Diablo Mephisto

Every 3rd hit from Lightning Nova against the same target deals 65 (+4% per level) bonus damage and grants Mephisto 2 Mana.

Mephisto Malicious Intent ✘︎
Malicious Intent (Level 1) Diablo Mephisto

Shade of Mephisto grants 25% Spell Power while active and for 2.5 seconds after ending.

If Mephisto hits enemy Heroes at least 18 times with his Basic Abilities while Shade of Mephisto is active, then increase the duration of the Spell Power bonus to 10 seconds after it ends.



Unyielding Power Icon Unyielding Power is a quest that enhances Skull Missile Icon Skull Missile upon completion of its components. It significantly increases Skull Missile's damage and lowers its cooldown. This Talent is a key piece for a Skull Missile Build.

Furious Spark Icon Furious Spark is a great way to increase the damage of Lightning Nova Icon Lightning Nova. It is very easy to trigger the bonus damage against most Heroes. This is especially true against lumbering frontline Warriors. Furious Spark is recommended Talent to go at level 1 as it gives the most damage increase.

Malicious Intent Icon Malicious Intent is an interesting option here. The instantly gained Spell power is decent, however, it lasts for a very short duration. Adding in the condition to hit enemy Heroes 18 times to extend the duration makes it a tough choice compared to the other two Talents. The damage increase provided by Furious Spark and Unyielding Power makes it so Malicious Intent is never worth picking.


Level 4 Talents for Mephisto

Mephisto Hateful Mending ✘︎
Hateful Mending (Level 4) Diablo Mephisto

Skull Missile grants 10 Mana and heals Mephisto for 70% of the damage it deals to Heroes.

Mephisto Static Barrier ?
Static Barrier (Level 4) Diablo Mephisto

At the end of its duration, Lightning Nova grants Mephisto a Shield equal to 40% of the damage it dealt to Heroes. Lasts 5 seconds.

Mephisto Spite
Spite (Level 4) Diablo Mephisto

Increase Regeneration Globe healing duration by 150%. Every tick of Regeneration Globe healing activates Lord of Hatred, reducing Basic Ability cooldowns by 1 second.



Hateful Mending Icon Hateful Mending is a healing option that is tied to Skull Missile. The healing provided by this Talent is very low when compared to Spite and lacks the utility. Hateful mending should not be picked at all.

Static Barrier Icon Static Barrier is very strong, as it will give you a Shield when you need it most. You will often be trading damage with enemy Heroes when Lightning Nova is used. With this Talent you will be able to stay on the offensive, when you would otherwise need to relent. Static Barrier provides Mephisto with self-sustain during combat, and is recommended for this reason.

While Spite Icon Spite itself reads as healing duration, it also increases the Mana Regeneration duration. This allows you to poke more often during the laning phase and you will find yourself very rarely having to hearthstone back to regenerate Mana. Regeneration Globes will also activate Lord Of Hatred Icon Lord Of Hatred.


Level 7 Talents for Mephisto

Mephisto Ghastly Armor ?
Ghastly Armor (Level 7) Diablo Mephisto

Shade of Mephisto grants 25 Armor while active and for 2.5 seconds after it ends.

Mephisto Frost Storm ?
Frost Storm (Level 7) Diablo Mephisto

While Shade of Mephisto is active, enemies who are hit by Lightning Nova are Slowed by 15% for 1 second and the Slow from Skull Missile is increased to 50%.

Mephisto Trickery
Trickery (Level 7) Diablo Mephisto

Shade of Mephisto grants 20% Movement Speed while active and for 2.5 seconds after it ends.

If Mephisto hits enemy Heroes at least 18 times with his Basic Abilities while Shade of Mephisto is active, then reset the cooldown of Shade of Mephisto.



All Talents at Level 7 are great for Mephisto and tie down to certain situations or enemy compositions.

Ghastly Armor Icon Ghastly Armor should be picked if the enemy composition has Heroes that either counter you or are able to dish out alot of damage because you teleported into them. Abilities like Living Bomb Icon Living Bomb that do damage after shade has ended makes Ghastly Armor a great Talent.

Frost Storm Icon Frost Storm will allow you to greatly reduce the Movement Speed of enemy Heroes hit by Skull Missile. It also Slows enemies near Lightning Nova. This Talent is great if the enemy composition is stacked up or if they have Heroes with semi-decent mobility.

Trickery Icon Trickery is the most offensive option here, because the increased Movement Speed makes it much easier to apply Lightning Nova to enemy Heroes. This Talent is great if the enemy composition consists of Heroes with great mobility that you would need to chase down with your Abilities.


Level 10 Talents for Mephisto

Mephisto Consume Souls ?
Consume Souls (Level 10) Diablo Mephisto
  • Mana: 80
  • Cooldown: 120 seconds

Channel for 2.5 seconds, revealing all enemy Heroes. After the Channel completes, all enemy Heroes take 357 (+4% per level) damage and are Slowed by 25% for 2.5 seconds.

Mephisto Durance of Hate
Durance of Hate (Level 10) Diablo Mephisto
  • Mana: 50
  • Cooldown: 50 seconds

After 1 second, unleash a wave of evil spirits that Root the first enemy Hero hit for 2.5 seconds and deal 250 (+4% per level) damage to them over the same duration.

Durance of Hate spreads outwards from its initial target, Rooting and damaging additional nearby enemy Heroes.



At this Level, you gain access to Heroic Abilities. If you want to read more about them, check the dedicated section in the Abilities and Strategy page.

Consume Souls Icon Consume Souls will damage, Slow, and reveal all enemy Heroes. This can only be avoided by Heroes that can prevent damage with Shields, enter Stasis, or temporarily exit the Map. It is an extremely reliable effect, and works well with most Heroic Ability chains. This Talent is also great for when enemy Heroes manage to slither out with a tiny amount of Health, allowing you to safely get a kill.

Durance of Hate Icon Durance of Hate is a great Talent and allows your team to follow-up on a target you hit with Durance of Hate. Durance of Hate will also spread out from the initial target, allowing Mephisto to Root several targets if used correctly. This Talent alone can be the difference of a lost or won teamfight.


Level 13 Talents for Mephisto

Mephisto Abhorred Skull
Abhorred Skull (Level 13) Diablo Mephisto

Hitting a Hero with Skull Missile grants 25% Spell Power for 6 seconds. Skull Missile deals 40% more damage to Heroes under 50% Health.

Mephisto Hysteria ?
Hysteria (Level 13) Diablo Mephisto

Lord of Hatred also reduces the cooldown of Mephisto's Heroic Ability. Mephisto is healed for 15% of his maximum Health and Mana when he casts his Heroic Ability.

Mephisto Shard of Hate ?
Shard of Hate (Level 13) Diablo Mephisto

Basic Attacks hit enemies near the primary target and activate Lord of Hatred against enemy Heroes, reducing Basic Ability cooldowns by 1 second per Hero hit.



Abhorred Skull Icon Abhorred Skull grants Spell Power whenever an enemy Hero is hit by Skull Missile, and the extra damage to an enemy Hero below 50% Health adds a little bit of extra damage to Skull Missile. Most Skull Missile Talents only work well as part of a Skull Missile Build, but this Talent can be very strong in other Builds as well.

Hysteria Icon Hysteria allows you to reduce your Heroic cooldown with Lord of Hatred. Hysteria has great synergy with Mephisto's level 4 Talent Spite Icon Spite, meaning every healing tick from Regneration Globes also reduces the cooldown of your Heroic Ability. This pairs greatly with both Consume Souls and Durance of Hate, allowing you to cast them more often throughout a game.

Shard of Hate Icon Shard of Hate causes your Basic Attacks to trigger Lord of Hatred and splash to enemy Heroes nearby the initial target. This is a great Talent for both waveclearing and teamfighting. In teamfights Shard of Hate will allowing you to further reduce the cooldown of your Basic Abilities and will greatly increase the damage you can dish out during a Shade.


Level 16 Talents for Mephisto

Mephisto Lightning Reaction
Lightning Reaction (Level 16) Diablo Mephisto

Skull Missile explodes on contact with Lightning Nova, dealing 138 (+4% per level) damage to nearby enemies.

Mephisto Static Field ?
Static Field (Level 16) Diablo Mephisto

When Lightning Nova's damage bonus reaches 30%, enemy Heroes within its radius take damage equal to 10% of their maximum Health.

Mephisto Animosity ✘︎
Animosity (Level 16) Diablo Mephisto

Increase the duration of Lightning Nova by 1 second and the maximum amount of bonus damage it can deal from 30% to 42%.



Lightning Reaction Icon Lightning Reaction is quite strong when it works. The issue with it is the difficulty of getting it to work when (and where) you need it to. Skull Missile is a slow moving projectile that is launched from the casting location after a relatively long delay. A lot can change from the time you cast it, to the time it arrives were you wanted it to go. It may be helpful to practice with this Talent in Try Mode, where you can disable cooldowns and get a feel for it more quickly.

Static Field Icon Static Field can generate huge bursts of damage, especially when multiple enemy Heroes are hit by its effect. Static Field will damage all enemy Heroes within Lightning Nova's radius, not just the enemies hit by Lightning Nova. When picking Static Field, it is important to focus on hitting multiple targets with your Nova to trigger Static Field.

Animosity Icon Animosity is an interesting way to increase Lightning Nova's damage. Animosity falls just short of Static Field, primarily because it does not damage enemies inside of Lightning Nova.


Level 20 Talents for Mephisto

Mephisto Consumed by Hatred ?
Consumed by Hatred (Level 20) Diablo Mephisto

Consume Souls deals bonus damage equal to 10% of the target's missing Health. If Consume Souls initial cast kills a Hero it will cast 1 additional time.

Mephisto Unspeakable Horror ?
Unspeakable Horror (Level 20) Diablo Mephisto

Durance of Hate Silences enemies while they are Rooted and for 3 seconds after its Root expires.

Mephisto Mimic
Mimic (Level 20) Diablo Mephisto

While both Shade of Mephisto and Lightning Nova are active, Lightning Nova also casts from the Shade's location.

Mephisto Shade Lord ✘︎
Shade Lord (Level 20) Diablo Mephisto
  • Cooldown: 20 seconds

Activate to swap locations with Shade of Mephisto and refresh its duration.

Passive: Shade of Mephisto benefits from all of Mephisto's level 7 Talents.



Consumed by Hatred Icon Consumed by Hatred turns Consume Souls Icon Consume Souls into a global execute that repeats if a Hero is killed by the initial blast. When picking this Talent, it is very important to time your Consume Soul so that you kill an enemy Hero with it, allowing you to get a free Consume Souls in.

Unspeakable Horror Icon Unspeakable Horror is an extremely powerful upgrade for Durance of Hate, but this value can be lost if Durance of Hate does not hit an enemy Hero.

Mimic Icon Mimic makes it possible to cast two Lightning Novas at the same time. Thanks to Lord Of Hatred Icon Lord Of Hatred, this will often reset all of your Basic Abilities. Mimic is very powerful when combined with Static Barrier Icon Static Barrier and Static Field Icon Static Field. This would be the most recommended Talent due to the damage increase Mimic will give you.

Shade Lord Icon Shade Lord is a great survivability Talent for Mephisto, as it turns Shade of Mephisto into a proper escape. In addition, it opens up many plays that are not otherwise possible, however, due to not being a pure damage upgrade unlike the other Talents, it does not see much play.



  • 07 Mar. 2021: Guide has been updated with talents and builds.
  • 06 Dec. 2020: Guide has been updated with a new build. Changed Lightning Nova build talents.
  • 09 Nov. 2020: Guide has been reviewed and no changes are needed.
  • 19 Jul. 2020: Guide has been reviewed no changes are needed.
  • 14 Apr. 2020: Updated talents and build.
  • 12 Jul. 2019: Removed reference to Talent "Anger" which was removed in balance patch. Updated text on rebalanced Talents.
  • 26 Nov. 2018: Updated Talent discussion to reflect meta developments.
  • 12 Sep. 2018: Updated Talent discussion to reflect meta developments.
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